FEV_KEGG.Experiments.04 module¶

Question¶

Which enzymes, independent from substrate/product, are present in eco00260, but not in eco01100?

Method¶

Download pathway definition as KGML.
Convert to substance-reaction graph.
Convert to substance-gene graph.
Convert to substance-enzyme graph
Get set of enzymes for each graph.
Calculate difference of enzyme sets.
Print enzymes (gene name, enzyme name, all associated EC numbers, enzyme long name).

Result¶

3 results
b2366 dsdA [4.3.1.18] D-serine dehydratase
b3616 tdh [1.1.1.103] threonine 3-dehydrogenase
b3617 kbl [2.3.1.29] glycine C-acetyltransferase

Conclusion¶

Global map 01100 does not necessarily contain all enzymes for an organism.